Complications and Pathophysiology of COVID-19 in the Nervous System

Complications and Pathophysiology of COVID-19 in the Nervous System

The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global public health threat. Majority of the patients with COVID-19 have fever, cough, and fatigue. Critically ill patients can develop dyspnea and acute respiratory...

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Main Authors: Haiyang Yu, Tong Sun, Juan Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Neurology
Subjects:
coronavirus
COVID-19
SARS-CoV-2
nervous system
complication
pathophysiology
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.573421/full
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spelling doaj-246cdddf13df4a03b24a16c192da9ad92020-12-08T08:34:23ZengFrontiers Media S.A.Frontiers in Neurology1664-22952020-12-011110.3389/fneur.2020.573421573421Complications and Pathophysiology of COVID-19 in the Nervous SystemHaiyang Yu0Tong Sun1Juan Feng2Department of Neurology, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang, ChinaThe coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global public health threat. Majority of the patients with COVID-19 have fever, cough, and fatigue. Critically ill patients can develop dyspnea and acute respiratory distress syndrome. In addition to respiratory symptoms, neurological damage also occurs in some patients. However, the mechanisms by which SARS-CoV-2 invades the nervous system have not been elucidated yet. In order to provide some reference for designing optimal therapeutic strategies, we have discussed the complications and potential mechanisms of COVID-19 in the nervous system in this review.https://www.frontiersin.org/articles/10.3389/fneur.2020.573421/fullcoronavirusCOVID-19SARS-CoV-2nervous systemcomplicationpathophysiology
collection DOAJ
language English
format Article
sources DOAJ
author Haiyang Yu
Tong Sun
Juan Feng
spellingShingle Haiyang Yu
Tong Sun
Juan Feng
Complications and Pathophysiology of COVID-19 in the Nervous System
Frontiers in Neurology
coronavirus
COVID-19
SARS-CoV-2
nervous system
complication
pathophysiology
author_facet Haiyang Yu
Tong Sun
Juan Feng
author_sort Haiyang Yu
title Complications and Pathophysiology of COVID-19 in the Nervous System
title_short Complications and Pathophysiology of COVID-19 in the Nervous System
title_full Complications and Pathophysiology of COVID-19 in the Nervous System
title_fullStr Complications and Pathophysiology of COVID-19 in the Nervous System
title_full_unstemmed Complications and Pathophysiology of COVID-19 in the Nervous System
title_sort complications and pathophysiology of covid-19 in the nervous system
publisher Frontiers Media S.A.
series Frontiers in Neurology
issn 1664-2295
publishDate 2020-12-01
description The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global public health threat. Majority of the patients with COVID-19 have fever, cough, and fatigue. Critically ill patients can develop dyspnea and acute respiratory distress syndrome. In addition to respiratory symptoms, neurological damage also occurs in some patients. However, the mechanisms by which SARS-CoV-2 invades the nervous system have not been elucidated yet. In order to provide some reference for designing optimal therapeutic strategies, we have discussed the complications and potential mechanisms of COVID-19 in the nervous system in this review.
topic coronavirus
COVID-19
SARS-CoV-2
nervous system
complication
pathophysiology
url https://www.frontiersin.org/articles/10.3389/fneur.2020.573421/full
work_keys_str_mv AT haiyangyu complicationsandpathophysiologyofcovid19inthenervoussystem
AT tongsun complicationsandpathophysiologyofcovid19inthenervoussystem
AT juanfeng complicationsandpathophysiologyofcovid19inthenervoussystem
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