Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification
Abstract Skeletal fractures can result when there are co-morbid conditions that negatively impact bone strength. Fractures represent an important source of morbidity and mortality, especially in older populations. Diabetes mellitus is a metabolic disorder that has reached worldwide epidemic proporti...
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Online Access: | http://link.springer.com/article/10.1186/s40842-018-0060-9 |
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doaj-246bc7c124d340bda77e58ca7991deff2020-11-25T01:02:31ZengBMCClinical Diabetes and Endocrinology2055-82602018-04-01411810.1186/s40842-018-0060-9Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratificationRodrigo J. Valderrábano0Maria I. Linares1University of Miami Miller School of MedicineUniversity of Miami Miller School of MedicineAbstract Skeletal fractures can result when there are co-morbid conditions that negatively impact bone strength. Fractures represent an important source of morbidity and mortality, especially in older populations. Diabetes mellitus is a metabolic disorder that has reached worldwide epidemic proportions and is increasingly being recognized as a risk factor for fracture. Type 1 and Type 2 diabetes have different effects on bone mineral density but share common pathways, which lead to bone fragility. In this review, we discuss the available data on diabetes and fractures, bone density and the clinical implications for fracture risk stratification in current practice.http://link.springer.com/article/10.1186/s40842-018-0060-9Diabetes mellitusType 1 diabetes mellitusType 2 diabetes mellitusBone mineral densityFractureFracture risk stratification |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rodrigo J. Valderrábano Maria I. Linares |
spellingShingle |
Rodrigo J. Valderrábano Maria I. Linares Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification Clinical Diabetes and Endocrinology Diabetes mellitus Type 1 diabetes mellitus Type 2 diabetes mellitus Bone mineral density Fracture Fracture risk stratification |
author_facet |
Rodrigo J. Valderrábano Maria I. Linares |
author_sort |
Rodrigo J. Valderrábano |
title |
Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification |
title_short |
Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification |
title_full |
Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification |
title_fullStr |
Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification |
title_full_unstemmed |
Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification |
title_sort |
diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification |
publisher |
BMC |
series |
Clinical Diabetes and Endocrinology |
issn |
2055-8260 |
publishDate |
2018-04-01 |
description |
Abstract Skeletal fractures can result when there are co-morbid conditions that negatively impact bone strength. Fractures represent an important source of morbidity and mortality, especially in older populations. Diabetes mellitus is a metabolic disorder that has reached worldwide epidemic proportions and is increasingly being recognized as a risk factor for fracture. Type 1 and Type 2 diabetes have different effects on bone mineral density but share common pathways, which lead to bone fragility. In this review, we discuss the available data on diabetes and fractures, bone density and the clinical implications for fracture risk stratification in current practice. |
topic |
Diabetes mellitus Type 1 diabetes mellitus Type 2 diabetes mellitus Bone mineral density Fracture Fracture risk stratification |
url |
http://link.springer.com/article/10.1186/s40842-018-0060-9 |
work_keys_str_mv |
AT rodrigojvalderrabano diabetesmellitusandbonehealthepidemiologyetiologyandimplicationsforfractureriskstratification AT mariailinares diabetesmellitusandbonehealthepidemiologyetiologyandimplicationsforfractureriskstratification |
_version_ |
1725204404506722304 |