Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification

Abstract Skeletal fractures can result when there are co-morbid conditions that negatively impact bone strength. Fractures represent an important source of morbidity and mortality, especially in older populations. Diabetes mellitus is a metabolic disorder that has reached worldwide epidemic proporti...

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Main Authors: Rodrigo J. Valderrábano, Maria I. Linares
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Clinical Diabetes and Endocrinology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40842-018-0060-9
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spelling doaj-246bc7c124d340bda77e58ca7991deff2020-11-25T01:02:31ZengBMCClinical Diabetes and Endocrinology2055-82602018-04-01411810.1186/s40842-018-0060-9Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratificationRodrigo J. Valderrábano0Maria I. Linares1University of Miami Miller School of MedicineUniversity of Miami Miller School of MedicineAbstract Skeletal fractures can result when there are co-morbid conditions that negatively impact bone strength. Fractures represent an important source of morbidity and mortality, especially in older populations. Diabetes mellitus is a metabolic disorder that has reached worldwide epidemic proportions and is increasingly being recognized as a risk factor for fracture. Type 1 and Type 2 diabetes have different effects on bone mineral density but share common pathways, which lead to bone fragility. In this review, we discuss the available data on diabetes and fractures, bone density and the clinical implications for fracture risk stratification in current practice.http://link.springer.com/article/10.1186/s40842-018-0060-9Diabetes mellitusType 1 diabetes mellitusType 2 diabetes mellitusBone mineral densityFractureFracture risk stratification
collection DOAJ
language English
format Article
sources DOAJ
author Rodrigo J. Valderrábano
Maria I. Linares
spellingShingle Rodrigo J. Valderrábano
Maria I. Linares
Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification
Clinical Diabetes and Endocrinology
Diabetes mellitus
Type 1 diabetes mellitus
Type 2 diabetes mellitus
Bone mineral density
Fracture
Fracture risk stratification
author_facet Rodrigo J. Valderrábano
Maria I. Linares
author_sort Rodrigo J. Valderrábano
title Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification
title_short Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification
title_full Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification
title_fullStr Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification
title_full_unstemmed Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification
title_sort diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification
publisher BMC
series Clinical Diabetes and Endocrinology
issn 2055-8260
publishDate 2018-04-01
description Abstract Skeletal fractures can result when there are co-morbid conditions that negatively impact bone strength. Fractures represent an important source of morbidity and mortality, especially in older populations. Diabetes mellitus is a metabolic disorder that has reached worldwide epidemic proportions and is increasingly being recognized as a risk factor for fracture. Type 1 and Type 2 diabetes have different effects on bone mineral density but share common pathways, which lead to bone fragility. In this review, we discuss the available data on diabetes and fractures, bone density and the clinical implications for fracture risk stratification in current practice.
topic Diabetes mellitus
Type 1 diabetes mellitus
Type 2 diabetes mellitus
Bone mineral density
Fracture
Fracture risk stratification
url http://link.springer.com/article/10.1186/s40842-018-0060-9
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AT mariailinares diabetesmellitusandbonehealthepidemiologyetiologyandimplicationsforfractureriskstratification
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