Entropy and Fractal Dimension Study of the TDP-43 Protein Low Complexity Domain Sequence in ALS Disease Severity and SARS-CoV-2 Gene Sequences in Virulence Variability

Entropy and Fractal Dimension Study of the TDP-43 Protein Low Complexity Domain Sequence in ALS Disease Severity and SARS-CoV-2 Gene Sequences in Virulence Variability

The low complexity domain (LCD) sequence has been defined in terms of entropy using a 12 amino acid sliding window along a protein sequence in the study of disease-related genes. The amyotrophic lateral sclerosis (ALS)-related TDP-43 protein sequence with intra-LCD structural information based on cr...

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Bibliographic Details
Main Authors: Sunil Dehipawala, Eric Cheung, George Tremberger, Tak Cheung
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Entropy
Subjects:
entropy
fractal dimension
TDP-43
low complexity domain sequence
SARS-CoV-2
HAR1
Online Access:https://www.mdpi.com/1099-4300/23/8/1038

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