The role of Toll-like receptor 4 in apoptosis of brain tissue after induction of intracerebral hemorrhage

The role of Toll-like receptor 4 in apoptosis of brain tissue after induction of intracerebral hemorrhage

Abstract Background Inflammation and apoptosis caused by intracerebral hemorrhage (ICH) are two important factors that affect patient prognosis and survival. Toll-like receptor 4 (TLR4) triggers activation of the inflammatory pathway, causing synthesis and release of inflammatory factors. The inflam...

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Bibliographic Details
Main Authors: Xiaowei Fei, Yeting He, Jia Chen, Weitao Man, Chen Chen, Kai Sun, Boyun Ding, Chongwu Wang, Ruxiang Xu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
Toll-like receptor 4
Apoptosis
Intracerebral hemorrhage
TNF-α
IL-1β
Online Access:http://link.springer.com/article/10.1186/s12974-019-1634-x

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