Probing Context-Dependent Modulations of Ipsilateral Premotor-Motor Connectivity in Relapsing-Remitting Multiple Sclerosis

Probing Context-Dependent Modulations of Ipsilateral Premotor-Motor Connectivity in Relapsing-Remitting Multiple Sclerosis

Objective: We employed dual-site TMS to test whether ipsilateral functional premotor-motor connectivity is altered in relapsing-remitting Multiple Sclerosis (RR-MS) and is related to central fatigue.Methods: Twelve patients with RR-MS and 12 healthy controls performed a visually cued Pinch-NoPinch t...

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Bibliographic Details
Main Authors: Elisa Ruiu, Raffaele Dubbioso, Kristoffer Hougaard Madsen, Olivia Svolgaard, Estelle Raffin, Kasper Winther Andersen, Anke Ninija Karabanov, Hartwig Roman Siebner
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
dual-site TMS
fatigue
movement preparation
dorsal premotor cortex
primary motor cortex
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00193/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00193/full

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