Unliganded Progesterone Receptor Governs Estrogen Receptor Gene Expression by Regulating DNA Methylation in Breast Cancer Cells

Unliganded Progesterone Receptor Governs Estrogen Receptor Gene Expression by Regulating DNA Methylation in Breast Cancer Cells

Breast cancer prognosis and response to endocrine therapy strongly depends on the expression of the estrogen and progesterone receptors (ER and PR, respectively). Although much is known about ERα gene (ESR1) regulation after hormonal stimulation, how it is regulated in hormone-free conditi...

Full description

Bibliographic Details
Main Authors:	Gaetano Verde, Lara I. De Llobet, Roni H.G. Wright, Javier Quilez, Sandra Peiró, François Le Dily, Miguel Beato
Format:	Article
Language:	English
Published:	MDPI AG 2018-10-01
Series:	Cancers
Subjects:	progesterone receptor estrogen receptor gene expression DNA methylation breast cancer endocrine therapy
Online Access:	http://www.mdpi.com/2072-6694/10/10/371

Similar Items

Estrogen and progesterone receptor expression in breast carcinoma
by: TB Pathak, et al.
Published: (2011-10-01)

Expression of estrogen and progesterone receptors in subcutaneous endometriosis
by: Đorđević M., et al.
Published: (2010-01-01)

Immunohistochemical evaluation of estrogen and progesterone receptors in peripheral and central giant cell granuloma of the jaws
by: Razavi SM, et al.
Published: (2006-07-01)

Expression of estrogen and progesterone receptors in astrocytomas: a literature review
by: Cléciton Braga Tavares, et al.

Physiological factors affecting ovine uterine estrogen and progesterone receptor concentrations
by: Prater, Patrice L.
Published: (2013)

Distribution of estrogen and progesterone receptors in the primate ovary, with emphasis on subpopulations of cells within the corpus luteum.
by: Hild-Petito, Sheri Ann.
Published: (1988)

Immunohistochemical research of estrogen and progesterone receptors in the foci of retrocervical endometriosis
by: I. Yu. Oliynyk
Published: (2012-12-01)

Estrogen and Progesterone Receptor Expression and its Correlation with Various Clinicopathological Parameters in Ovarian Tumors
by: Shilpa Garg, et al.
Published: (2014-03-01)

Expression of Estrogen and Progesterone Receptors in Papillary Thyroid Carcinoma
by: Mohammadreza Jalali-Nadoushan, et al.
Published: (2016-07-01)

Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
by: Fabio Augusto Ito, et al.
Published: (2009-12-01)

Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal gland
by: Gligorijević Jasmina, et al.
Published: (2011-01-01)

Concordant Expression of Estrogen and Progesterone Receptors in Primary and Loco-regional Recurrent Breast Cancer
by: Sedigheh Tahmasebi, et al.
Published: (2013-07-01)

Immunohistochemical Analysis of Estrogen and Progesterone Receptor Expression in Gingival Lesions
by: F Agha-Hosseini, et al.
Published: (2006-06-01)

Immunohistochemical Analysis of Estrogen and Progesterone Receptor Expression in Gingival Lesions
by: F Agha-Hosseini, et al.
Published: (2006-06-01)

Profiling estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2/neu in breast carcinoma: Study of 111 consecutive cases
by: Muninder Negi, et al.
Published: (2018-01-01)

Change of serum and tissue estrogen and progesterone receptor, VEGF and its receptors in patients with endometriosis
by: Ling Kang, et al.
Published: (2016-11-01)

Interrelation of aromatase, estrogen receptor alpha and progesterone receptor in the developing mouse fetal brain
by: Mehmet Bertan Yilmaz, et al.
Published: (2013-04-01)

Differential expression of androgen, estrogen, and progesterone receptors in benign prostatic hyperplasia
by: Lingmin Song, et al.
Published: (2016-07-01)

Distribution of estrogen and progesterone receptors in Epulis Fissuratum
by: Shahrabi Sh., et al.
Published: (2005-06-01)

Investigating Estrogen and Progesterone Receptors in the Lacrimal Sacs of Individuals With and Without Chronic Dacryocystitis
by: Hakan Baybora, et al.
Published: (2019-04-01)

Immunohistochemical expression of estrogen and progesterone receptors in endometrial hyperplasia and endometrioid carcinoma
by: Sarmadi S, et al.
Published: (2012-06-01)

Evaluating Association of Tissue Selenium Level and Estrogen Receptor and Progesterone Receptor Expression in Breast Cancer
by: Sanaz Salar Amoli, et al.
Published: (2019-03-01)

Comparison of Estrogen Receptor and Progesterone Receptor in Ductal Carcinoma and Lobular Carcinoma With Regard to Age Prevalence
by: Seyed Morteza Mousavi Naeini, et al.
Published: (2017-08-01)

Amongst Women Stratified to Receive Endocrine Therapy on the Basis of Their Tumor Estrogen and Progesterone Receptor Levels, Those with Higher Tumor Progesterone Receptor Levels Had a Better Outcome than Those with Lower Levels of Tumor Progesterone Receptor
by: Tai-Han Lin, et al.
Published: (2021-02-01)

Advances in Variations of Estrogen Receptor, Progesterone Receptor and Human Epidermal Growth Factor Receptor-2 Status in Metastatic Breast Cancer
by: Yuan Yuan, et al.
Published: (2013-06-01)

Estrogen Receptor Positive/Progesterone Receptor Negative Breast Carcinomas: A Subgroup Deserves Particular Interest
by: Zühal GÜCİN, et al.
Published: (2015-08-01)

Immunoexpression of estrogen receptor-β and progesterone receptor in prostate adenocarcinoma, does it inhibit neoplastic proliferation and invasion?
by: Kinjal N Bera, et al.
Published: (2020-01-01)

Overexpression of estrogen and progesterone receptors as indicator of endometrial receptivity disorder in women with early miscarriage
by: Sergey S. Aganezov, et al.
Published: (2020-06-01)

Estrogen and Progesterone Receptor Immunoexpression in Fallopian Tubes among Postmenopausal Women Based on Time since the Last Menstrual Period
by: Agnieszka Brodowska, et al.
Published: (2021-08-01)

Differential expression of estrogen receptor α and progesterone receptor in the normal and cryptorchid testis of a dog
by: Hyo Young Jung, et al.
Published: (2016-12-01)

Study of Estrogen Receptor, Progesterone Receptor and Human Epidermal Growth Factor Receptor Expression by Immunohistochemistry in Breast Carcinoma
by: Saroj Deoghare, et al.
Published: (2018-01-01)

Estrogen and progesterone receptor testing in breast carcinoma: concordance of results between local and reference laboratories in Brazil
by: Sheila Cristina Lordelo Wludarski, et al.

Correlation of estrogen and progesterone receptors ER and PR expression with the growth of endometrial cancer
by: Xiang-Zhuan Gao, et al.
Published: (2017-07-01)

Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models
by: Rayna Rosati, et al.
Published: (2020-06-01)

Endometrial expression of leukemia inhibitory factor in women with different estrogen/progesterone receptor status of the endometrium
by: S. S. Aganezov, et al.
Published: (2019-07-01)

Estrogen and progesterone receptors in human papilloma virus-related cervical neoplasia
by: F.R.G. Coelho, et al.
Published: (2004-01-01)

p53, estrogen and progesterone receptors in diagnostic curettage for endometrial adenocarcinoma and their correlation with morphological data and disease stage at hysterectomy
by: Vera Lúcia Leite Bonfitto, et al.

Expression of androgen, estrogen, and progesterone hormone receptors in the penile tissues of children with different types of hypospadias
by: Ayşenur Celayir, et al.
Published: (2019-06-01)

Correlation of interleukin 6 (IL-6) with estrogen and progesterone receptor expression in breast cancer patients
by: Amal K. Chaloob
Published: (2011-01-01)

Sodium iodide symporter, estrogen receptor, and progesterone receptor expression in carcinoma breast - An immunohistochemical analysis
by: Ashwani Tandon, et al.
Published: (2011-01-01)

Cannot write session to /tmp/vufind_sessions/sess_vsnpoe5k39grb2og8k4gmbhnnv