Functional studies of ssDNA binding ability of MarR family protein TcaR from Staphylococcus epidermidis.

Functional studies of ssDNA binding ability of MarR family protein TcaR from Staphylococcus epidermidis.

The negative transcription regulator of the ica locus, TcaR, regulates proteins involved in the biosynthesis of poly-N-acetylglucosamine (PNAG). Absence of TcaR increases PNAG production and promotes biofilm formation in Staphylococci. Previously, the 3D structure of TcaR in its apo form and its com...

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Bibliographic Details
Main Authors: Yu-Ming Chang, Cammy K-M Chen, Yuan-Chih Chang, Wen-Yih Jeng, Ming-Hon Hou, Andrew H-J Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3448645?pdf=render

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