Spontaneous detachment of the leading head contributes to myosin VI backward steps.

Spontaneous detachment of the leading head contributes to myosin VI backward steps.

Myosin VI is an ATP driven molecular motor that normally takes forward and processive steps on actin filaments, but also on occasion stochastic backward steps. While a number of models have attempted to explain the backwards steps, none offer an acceptable mechanism for their existence. We therefore...

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Bibliographic Details
Main Authors: Keigo Ikezaki, Tomotaka Komori, Toshio Yanagida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3601099?pdf=render

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