Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults

Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults

<p>Abstract</p> <p>Background</p> <p>Accumulating data suggest a novel role for bile acids (BAs) in modulating metabolic homeostasis. BA treatment has been shown to improve glucose tolerance and to increase energy expenditure in mice. Here, we investigated the relations...

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Bibliographic Details
Main Authors: Laville Martine, Guyomarc'h-Delasalle Béatrice, Disse Emmanuel, Pouteau Etienne, Zaïr Yassine, Chetiveaux Maud, Cariou Bertrand, Krempf Michel
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Nutrition & Metabolism
Subjects:
bile acids
insulin resistance
type 2 diabetes
FXR
TGR5
energy expenditure
hyperinsulinemic-euglycemic clamp
Online Access:http://www.nutritionandmetabolism.com/content/8/1/48

Internet

http://www.nutritionandmetabolism.com/content/8/1/48

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