Behavior of three hypocholesterolemic peptides from soy protein in an intestinal model based on differentiated Caco-2 cell

IAVPGEVA, IAVPTGVA, and LPYP, three peptides deriving from soy protein hydrolysis, inhibit the activity of 3-hydroxy-3-methylglutaryl CoA reductase (HMGCoAR) and modulate cholesterol metabolism in HepG2 cells. In order to assess whether these hypocholesterolemic peptides can be absorbed across the e...

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Bibliographic Details
Main Authors: Gilda Aiello, Simonetta Ferruzza, Giulia Ranaldi, Yula Sambuy, Anna Arnoldi, Giulio Vistoli, Carmen Lammi
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618301634