Upregulation of COX4-2 via HIF-1α in Mitochondrial COX4-1 Deficiency

Upregulation of COX4-2 via HIF-1α in Mitochondrial COX4-1 Deficiency

Cytochrome-<i>c</i>-oxidase (COX) subunit 4 (COX4) plays important roles in the function, assembly and regulation of COX (mitochondrial respiratory complex 4), the terminal electron acceptor of the oxidative phosphorylation (OXPHOS) system. The principal COX4 isoform, COX4-1, is expresse...

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Bibliographic Details
Main Authors: Liza Douiev, Chaya Miller, Shmuel Ruppo, Hadar Benyamini, Bassam Abu-Libdeh, Ann Saada
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
mitochondria
cytochrome <i>c</i> oxidase
COX4-1
COX4-2
HIF-1α
Online Access:https://www.mdpi.com/2073-4409/10/2/452

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