Functional and association studies on the pig HMGCR gene, a cholesterol-synthesis limiting enzyme
The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) is the rate-limiting enzyme in the biosynthesis of cholesterol. We have studied the role of the HMGCR gene in pig lipid metabolism by means of expression and structural analysis. We describe here the complete coding region of this gene in pigs and...
Main Authors: | A. Cánovas, R. Quintanilla, D. Gallardo, I. Díaz, J.L. Noguera, O. Ramírez, R.N. Pena |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-01-01
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Series: | Animal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1751731109991145 |
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