Using Hippophae rhamnoides leaf extract in the treatment of chicken pox in children

• Main Authors: S.O. Кramarov, V.V. Yevtushenko, V.O. Shadrin, E.V. Golovach, Т.M. Kaminskaya
• Format: Article
• Language: English
• Published: Publishing House Zaslavsky 2018-03-01
• Series: Aktualʹnaâ Infektologiâ
• Subjects: chicken pox; children; Hippophae rhamnoides extract
• Online Access: http://ai.zaslavsky.com.ua/article/view/131093

Background. In Ukraine, about 150 thousand children suffer from chicken pox every year. Symptomatic and supportive treatment is indicated for all forms of chicken pox. The purpose of the study was to evaluate the efficacy and tolerability of Hippophae rhamnoides (Erebra) extract in the comprehensive treatment of chicken pox in children. Materials and methods. Research design: prospective, open-label, controlled. The study involved children who underwent inpatient treatment with a diagnosis of chicken pox during 2017–2018. Patients in the main group received Hippophae rhamnoides extract in the combined treatment of chicken pox, standard symptomatic therapy was prescribed to control patients. Results. Sixty four children were examined, the main group consisted of 34 patients, control group — 30 individuals. On the background of therapy, a positive dynamics of clinical symptoms was observed in all patients. On day 5, fever was more frequently detected in controls than in the main group (50.0 vs 23.5 %, p < 0.05 according to the χ2 criterion). Disorders of the general state on day 3 of observation were noted in 55.8 % of children in the main group and in 86.7 % of controls (p < 0.05 according to χ2 criterion). Conclusions. The use of Hippophae rhamnoides extract in comprehensive therapy of children with chicken pox accelerates the norma­lization of clinical symptoms. The Hippophae rhamnoides extract has a high safety profile and is well tolerated.