Early Involvement of Immune/Inflammatory Response Genes in Retinal Degeneration in DBA/2J Mice

Early Involvement of Immune/Inflammatory Response Genes in Retinal Degeneration in DBA/2J Mice

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Purpose: The DBA/2J (D2) mouse carries mutations in two of its genes, Tyrp1 and Gpnmb. These alterations result in the development of an immune response in the iris, leading to iris atrophy and pigment dispersion. The development of elevated intraocular pressure (IOP) in this model of glaucoma is co...

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Bibliographic Details
Main Authors:	W. Fan, X. Li, W. Wang, J.S. Mo, H. Kaplan, N.G.F. Cooper
Format:	Article
Language:	English
Published:	SAGE Publishing 2010-03-01
Series:	Ophthalmology and Eye Diseases
Online Access:	http://la-press.com/early-involvement-of-immuneinflammatory-response-genes-in-retinal-dege-a1916

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