Augmented peroxisomal ROS buffering capacity renders oxidative and thermal stress cross-tolerance in yeast

Augmented peroxisomal ROS buffering capacity renders oxidative and thermal stress cross-tolerance in yeast

Abstract Background Thermotolerant yeast has outstanding potential in industrial applications. Komagataella phaffii (Pichia pastoris) is a common cell factory for industrial production of heterologous proteins. Results Herein, we obtained a thermotolerant K. phaffii mutant G14 by mutagenesis and ada...

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Bibliographic Details
Main Authors: Nai-Xin Lin, Rui-Zhen He, Yan Xu, Xiao-Wei Yu
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Microbial Cell Factories
Subjects:
Yeast
Komagataella phaffii
Thermotolerance
Reactive oxygen species (ROS)
Peroxisome
Catalase
Online Access:https://doi.org/10.1186/s12934-021-01623-1

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