Host Gene SEL1L Involved in Endoplasmic Reticulum-Associated Degradation Pathway Could Inhibit Hepatitis B Virus at RNA, DNA, and Protein Levels

Host Gene SEL1L Involved in Endoplasmic Reticulum-Associated Degradation Pathway Could Inhibit Hepatitis B Virus at RNA, DNA, and Protein Levels

Hepatitis B virus (HBV) belongs to the Hepadnaviridae family of enveloped DNA viruses. Recent studies have found that host factors can suppress HBV replication. HBV envelope proteins are reported to be degraded by the endoplasmic reticulum-associated degradation (ERAD) pathway. As a component of the...

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Bibliographic Details
Main Authors: Jinyu Wang, Jing Li, Jingwen Wu, Minhui Dong, Zhongliang Shen, Yong Lin, Fahong Li, Yongmei Zhang, Richeng Mao, Mengji Lu, Jiming Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Microbiology
Subjects:
hepatitis B virus
SEL1L
endoplasmic reticulum-associated degradation
endoplasmic reticulum quality control-autophagy
immune tolerant
inactive carrier
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02869/full

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