Nanoparticles with High-Surface Negative-Charge Density Disturb the Metabolism of Low-Density Lipoprotein in Cells

Endocytosis is an important pathway to regulate the metabolism of low-density lipoprotein (LDL) in cells. At the same time, engineering nanoparticles (ENPs) enter the cell through endocytosis in biomedical applications. Therefore, a crucial question is whether the nanoparticles involved in endocytos...

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Bibliographic Details
Main Authors: Xue Bai, Jiaxin Zhang, Ya-Nan Chang, Weihong Gu, Runhong Lei, Yanxia Qin, Shibo Xia, Sihan Ma, Yuelan Liang, Kui Chen, Juan Li, Baoyun Sun, Gengmei Xing
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/19/9/2790