Development and Application of Real-Time Quantitative Polymerase Chain Reaction Technique Using SYBR Green I in the Diagnosis of Down Syndrome

Development and Application of Real-Time Quantitative Polymerase Chain Reaction Technique Using SYBR Green I in the Diagnosis of Down Syndrome

Objective: Rapid diagnosis of Trisomy 21 Syndrome (Down Syndrome) patients usingReal-Time quantitative Polymerase Chain Reaction (Real-Time qPCR) in order to establisha novel method for prenatal diagnosis in the future.Materials and Methods: A total of 5 ml of peripheral blood was obtained from each...

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Bibliographic Details
Main Authors: Shirin Shahbazi, Ahmad Reza Kamyab, Reza Mahdian, Katayun Akhlagh Tamiz, Amir Reza Rafiee, Mohammad Taghi Akbari, Mina Hayt Nosaeid, Parvin Dibajnia
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2010-01-01
Series:Cell Journal
Subjects:
Down Syndrome
Trisomy 21
Gene Copy Number
Real-Time
PCR
Online Access:http://celljournal.org/library/upload/article/af_6653935Kamyab.pdf

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