Control of Melanogenesis In the Human Epidermis by the Redox-Status of Tetrahydrobiopterins

Activity of tyrosinase directly controls melanogenesis in the human epidermis. Recently, it has been shown that the biosynthesis and recycling of (6R)L-erythro 5,6,7,8 tetrahydrobiopterin (6-BH4) plays a central role in regulating the supply of L-tyrosine, the substrate for tyrosinase. In this repor...

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Bibliographic Details
Main Authors: Schallreuter-Wood Karin U., Wood John M.
Format: Article
Language:English
Published: De Gruyter 1995-08-01
Series:Pteridines
Online Access:https://doi.org/10.1515/pteridines.1995.6.3.101

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