Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis

ABSTRACT Ovarian cancer is the leading cause of gynecological malignancy-related deaths. Current therapies for ovarian cancer do not provide meaningful and sustainable clinical benefits, highlighting the need for new therapies. We show that the histone H3K79 methyltransferase disruptor of telomeric...

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Bibliographic Details
Main Authors: Suresh Chava, Suresh Bugide, Yvonne J. K. Edwards, Romi Gupta
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-021-00339-6