Contralateral risk-reducing local therapy in breast cancer patients with BRCA1/2 mutations: systemic review and meta-analysis

Contralateral risk-reducing local therapy in breast cancer patients with BRCA1/2 mutations: systemic review and meta-analysis

Abstract Background Unilateral breast cancer (UBC) patients with germline pathogenic BRCA1/2 variants have a higher risk of developing contralateral breast cancer (CBC) and need contralateral risk-reducing local treatments, including contralateral risk-reducing mastectomy (CRRM) and prophylactic irr...

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Bibliographic Details
Main Authors: Ziqi Jia, Jiaxin Li, Yuelun Zhang, Xin Wang, Jiahua Xing, Zeyu Xing, Xin Huang, Gang Liu, Menglu Zhang, Kexin Feng, Jiang Wu, Wenyan Wang, Jie Wang, Jiaqi Liu, Xiang Wang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cancer Cell International
Subjects:
BRCA1
BRCA2
Contralateral risk-reducing mastectomy
Contralateral prophylactic irradiation
Online Access:https://doi.org/10.1186/s12935-021-02194-2

Internet

https://doi.org/10.1186/s12935-021-02194-2

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