P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy.

P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy.

<h4>Background</h4>Duchenne muscular dystrophy (DMD) is the most common inherited muscle disease, leading to severe disability and death in young men. Death is caused by the progressive degeneration of striated muscles aggravated by sterile inflammation. The pleiotropic effects of the mu...

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Main Authors: Anthony Sinadinos, Christopher N J Young, Rasha Al-Khalidi, Anna Teti, Paweł Kalinski, Shafini Mohamad, Léonore Floriot, Tiphaine Henry, Gianluca Tozzi, Taiwen Jiang, Olivier Wurtz, Alexis Lefebvre, Mikhail Shugay, Jie Tong, David Vaudry, Stephen Arkle, Jean-Claude doRego, Dariusz C Górecki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1001888

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