The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer

The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer

HRAS, KRAS and NRAS gene products belong to the superfamily of small GTPases. These proteins regulate cellular response to extracellular stimuli by means of activation of different signaling pathways. Although the role of RAS gene mutations in the pathogenesis of various human cancers has been estab...

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Bibliographic Details
Main Authors: M. P. Smal, A. I. Rolevich, T. N. Nabebina, S. A. Krasny, R. I. Goncharova
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2015-12-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
bladder cancer
hras
kras
nras
snapshot
mutation
prognostic value
Online Access:https://vavilov.elpub.ru/jour/article/view/457

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