The Vascular-Targeting Fusion Toxin VEGF121/rGel Inhibits the Growth of Orthotopic Human Bladder Carcinoma Tumors

The Vascular-Targeting Fusion Toxin VEGF121/rGel Inhibits the Growth of Orthotopic Human Bladder Carcinoma Tumors

Vascular endothelial growth factor. (VEGF) and its receptors. (FLT-1 and KDR) are overexpressed by human bladder cancer cells and tumor endothelial cells, respectively. Strategies that target VEGF receptors hold promise as antlanglogenic therapeutic approaches to bladder cancer. A fusion protein of...

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Bibliographic Details
Main Authors: Khalid Mohamedali, Daniel Kedar, Paul Sweeney, Ashish Kamat, Darren W. Davis, Beryl Y. Eve, Samuel Huang, Philip E. Thorpe, Colin P. Dinney, Michael G. Rosenblum
Format: Article
Language:English
Published: Elsevier 2005-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Fusion toxin
VEGF
gelanin
vascular targeting
bladder cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605801150

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