Genetic Screening for Familial Gastric Cancer

Genetic Screening for Familial Gastric Cancer

<p>Abstract</p> <p>Approximately 10% of gastric cancer cases show familial clustering but only 1-3% of gastric carcinomas arise as a result of inherited gastric cancer predisposition syndromes. Direct proof that Hereditary Gastric Cancer a genetic disease with a germline gene defec...

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Bibliographic Details
Main Authors: Oliveira Carla, Suriano Gianpaolo, Ferreira Paulo, Canedo Paulo, Kaurah Pardeep, Mateus Rita, Ferreira Ana, Ferreira António C, Oliveira Maria, Figueiredo Céu, Carneiro Fátima, Keller Gisela, Huntsman David, Machado José, Seruca Raquel
Format: Article
Language:English
Published: BMC 2004-05-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
gastric cancer
familial gastric cancer
E-cadherin
CDH1
HDGC
hereditary diffuse gastric cancer
inheritance
germline mutation
missense mutation
Helicobacter pylori
low penetrance genes
IL1
TNFα
early onset
genetic counselling
functional analysis
Online Access:http://www.hccpjournal.com/content/2/2/51

Internet

http://www.hccpjournal.com/content/2/2/51

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