High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites

High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites

Mapping RNA accessibility is valuable for identifying functional/regulatory RNA regions. Here the authors introduce INTERFACE, an intracellular method that quantifies antisense hybridization efficacy of any number of RNA regions simultaneously via a transcriptional elongation output, measurable via...

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Bibliographic Details
Main Authors: Mia K. Mihailovic, Jorge Vazquez-Anderson, Yan Li, Victoria Fry, Praveen Vimalathas, Daniel Herrera, Richard A. Lease, Warren B. Powell, Lydia M. Contreras
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06207-z

Internet

https://doi.org/10.1038/s41467-018-06207-z

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