Encryption and steganography of synthetic gene circuits

Artificial gene circuits represent intellectual property that under some circumstances may need to be obfuscated to prevent discovery by third parties. Here the authors use encryption by overlapping recombinase sites and steganography by the introduction of superfluous components, to obscure circuit...

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Main Authors: Oliver Purcell, Jerry Wang, Piro Siuti, Timothy K. Lu
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07144-7
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spelling doaj-2348246b63d84468affce4ac99ff48102021-05-11T09:43:01ZengNature Publishing GroupNature Communications2041-17232018-11-019111010.1038/s41467-018-07144-7Encryption and steganography of synthetic gene circuitsOliver Purcell0Jerry Wang1Piro Siuti2Timothy K. Lu3Synthetic Biology Center, Massachusetts Institute of TechnologySynthetic Biology Center, Massachusetts Institute of TechnologySynthetic Biology Center, Massachusetts Institute of TechnologySynthetic Biology Center, Massachusetts Institute of TechnologyArtificial gene circuits represent intellectual property that under some circumstances may need to be obfuscated to prevent discovery by third parties. Here the authors use encryption by overlapping recombinase sites and steganography by the introduction of superfluous components, to obscure circuit topology.https://doi.org/10.1038/s41467-018-07144-7
collection DOAJ
language English
format Article
sources DOAJ
author Oliver Purcell
Jerry Wang
Piro Siuti
Timothy K. Lu
spellingShingle Oliver Purcell
Jerry Wang
Piro Siuti
Timothy K. Lu
Encryption and steganography of synthetic gene circuits
Nature Communications
author_facet Oliver Purcell
Jerry Wang
Piro Siuti
Timothy K. Lu
author_sort Oliver Purcell
title Encryption and steganography of synthetic gene circuits
title_short Encryption and steganography of synthetic gene circuits
title_full Encryption and steganography of synthetic gene circuits
title_fullStr Encryption and steganography of synthetic gene circuits
title_full_unstemmed Encryption and steganography of synthetic gene circuits
title_sort encryption and steganography of synthetic gene circuits
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-11-01
description Artificial gene circuits represent intellectual property that under some circumstances may need to be obfuscated to prevent discovery by third parties. Here the authors use encryption by overlapping recombinase sites and steganography by the introduction of superfluous components, to obscure circuit topology.
url https://doi.org/10.1038/s41467-018-07144-7
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