Lipopolysaccharide induces immune activation and SIV replication in rhesus macaques of Chinese origin.

BACKGROUND: Chronic immune activation is a hallmark of progressive HIV infection and a key determinant of immunodeficiency in HIV-infected individuals. Bacterial lipopolysaccharide (LPS) in the circulation has been implicated as a key factor in HIV infection-related systemic immune activation. We th...

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Bibliographic Details
Main Authors: Rong Bao, Ke Zhuang, Jinbiao Liu, Jianguo Wu, Jieliang Li, Xu Wang, Wen-Zhe Ho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4053387?pdf=render