Significant Quantitative Differences in Orexin Neuronal Activation After Pain Assessments in an Animal Model of Sickle Cell Disease
Sickle cell disease is a hemoglobinopathy that causes sickling of red blood cells, resulting in vessel blockage, stroke, anemia, inflammation, and extreme pain. The development and treatment of pain, in particular, neuropathic pain in sickle cell disease patients is poorly understood and impedes our...
Main Authors: | Kimberlei Richardson, Nia Sweatt, Huy Tran, Victor Apprey, Subramaniam Uthayathas, Robert Taylor, Kalpna Gupta |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-01-01
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Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fmolb.2020.00005/full |
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