Auto-FPFA: An Automated Microscope for Characterizing Genetically Encoded Biosensors
Abstract Genetically encoded biosensors function by linking structural change in a protein construct, typically tagged with one or more fluorescent proteins, to changes in a biological parameter of interest (such as calcium concentration, pH, phosphorylation-state, etc.). Typically, the structural c...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-05-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-25689-x |