Role of Prion Protein Aggregation in Neurotoxicity

In several neurodegenerative diseases, such as Parkinson, Alzheimer’s, Huntington, and prion diseases, the deposition of aggregated misfolded proteins is believed to be responsible for the neurotoxicity that characterizes these diseases. Prion protein (PrP), the protein responsible of prion diseases...

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Bibliographic Details
Main Authors: Tullio Florio, Mario Nizzari, Stefano Thellung, Valentina Villa, Alessandro Corsaro
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/13/7/8648