Intestinal Microbiota Promotes Psoriasis-Like Skin Inflammation by Enhancing Th17 Response.

Psoriasis is a chronic inflammatory skin disease in which Th17 cells play a crucial role. Since indigenous gut microbiota influences the development and reactivity of immune cells, we analyzed the link among microbiota, T cells and the formation of psoriatic lesions in the imiquimod-induced murine m...

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Bibliographic Details
Main Authors: Zuzana Zákostelská, Jana Málková, Klára Klimešová, Pavel Rossmann, Michaela Hornová, Iva Novosádová, Zuzana Stehlíková, Martin Kostovčík, Tomáš Hudcovic, Renata Štepánková, Kateřina Jůzlová, Jana Hercogová, Helena Tlaskalová-Hogenová, Miloslav Kverka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4951142?pdf=render