A Lanthanide-Based Chemosensor for Bioavailable Fe3+ Using a Fluorescent Siderophore: An Assay Displacement Approach

The measurement of trace analytes in aqueous systems has become increasingly important for understanding ocean primary productivity. In oceanography, iron (Fe) is a key element in regulating ocean productivity, microplankton assemblages and has been identified as a causative element in the developme...

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Main Authors:	Karl J. Wallace, David Schrock, Andrea McDonald, W. Scott Jones, Karen M. Orcutt
Format:	Article
Language:	English
Published:	MDPI AG 2010-02-01
Series:	Sensors
Subjects:	lanthanide desferrioxamine siderophore iron chemosensor indicator displacement assay
Online Access:	http://www.mdpi.com/1424-8220/10/2/1326/

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spelling	doaj-22e810d0057147e1a001bcb87597ace62020-11-24T23:34:33ZengMDPI AGSensors1424-82202010-02-011021326133710.3390/s100201326A Lanthanide-Based Chemosensor for Bioavailable Fe3+ Using a Fluorescent Siderophore: An Assay Displacement ApproachKarl J. WallaceDavid SchrockAndrea McDonaldW. Scott JonesKaren M. OrcuttThe measurement of trace analytes in aqueous systems has become increasingly important for understanding ocean primary productivity. In oceanography, iron (Fe) is a key element in regulating ocean productivity, microplankton assemblages and has been identified as a causative element in the development of some harmful algal blooms.The chemosenor developed in this study is based on an indicator displacement approach that utilizes time-resolved fluorescence and fluorescence resonance energy transfer as the sensing mechanism to achieve detection of Fe3+ ions as low as 5 nM. This novel approach holds promise for the development of photoactive chemosensors for ocean deployment. http://www.mdpi.com/1424-8220/10/2/1326/lanthanidedesferrioxaminesiderophoreironchemosensorindicator displacement assay
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Karl J. Wallace David Schrock Andrea McDonald W. Scott Jones Karen M. Orcutt
spellingShingle	Karl J. Wallace David Schrock Andrea McDonald W. Scott Jones Karen M. Orcutt A Lanthanide-Based Chemosensor for Bioavailable Fe3+ Using a Fluorescent Siderophore: An Assay Displacement Approach Sensors lanthanide desferrioxamine siderophore iron chemosensor indicator displacement assay
author_facet	Karl J. Wallace David Schrock Andrea McDonald W. Scott Jones Karen M. Orcutt
author_sort	Karl J. Wallace
title	A Lanthanide-Based Chemosensor for Bioavailable Fe3+ Using a Fluorescent Siderophore: An Assay Displacement Approach
title_short	A Lanthanide-Based Chemosensor for Bioavailable Fe3+ Using a Fluorescent Siderophore: An Assay Displacement Approach
title_full	A Lanthanide-Based Chemosensor for Bioavailable Fe3+ Using a Fluorescent Siderophore: An Assay Displacement Approach
title_fullStr	A Lanthanide-Based Chemosensor for Bioavailable Fe3+ Using a Fluorescent Siderophore: An Assay Displacement Approach
title_full_unstemmed	A Lanthanide-Based Chemosensor for Bioavailable Fe3+ Using a Fluorescent Siderophore: An Assay Displacement Approach
title_sort	lanthanide-based chemosensor for bioavailable fe3+ using a fluorescent siderophore: an assay displacement approach
publisher	MDPI AG
series	Sensors
issn	1424-8220
publishDate	2010-02-01
description	The measurement of trace analytes in aqueous systems has become increasingly important for understanding ocean primary productivity. In oceanography, iron (Fe) is a key element in regulating ocean productivity, microplankton assemblages and has been identified as a causative element in the development of some harmful algal blooms.The chemosenor developed in this study is based on an indicator displacement approach that utilizes time-resolved fluorescence and fluorescence resonance energy transfer as the sensing mechanism to achieve detection of Fe3+ ions as low as 5 nM. This novel approach holds promise for the development of photoactive chemosensors for ocean deployment.
topic	lanthanide desferrioxamine siderophore iron chemosensor indicator displacement assay
url	http://www.mdpi.com/1424-8220/10/2/1326/
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A Lanthanide-Based Chemosensor for Bioavailable Fe3+ Using a Fluorescent Siderophore: An Assay Displacement Approach

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