Transcriptomic Analysis of Inbred Chicken Lines Reveals Infectious Bursal Disease Severity Is Associated with Greater Bursal Inflammation In Vivo and More Rapid Induction of Pro-Inflammatory Responses in Primary Bursal Cells Stimulated Ex Vivo

Transcriptomic Analysis of Inbred Chicken Lines Reveals Infectious Bursal Disease Severity Is Associated with Greater Bursal Inflammation In Vivo and More Rapid Induction of Pro-Inflammatory Responses in Primary Bursal Cells Stimulated Ex Vivo

In order to better understand differences in the outcome of infectious bursal disease virus (IBDV) infection, we inoculated a very virulent (vv) strain into White Leghorn chickens of inbred line W that was previously reported to experience over 24% flock mortality, and three inbred lines (15I, C.B4...

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Bibliographic Details
Main Authors: Amin S. Asfor, Salik Nazki, Vishwanatha R.A.P. Reddy, Elle Campbell, Katherine L. Dulwich, Efstathios S. Giotis, Michael A. Skinner, Andrew J. Broadbent
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Viruses
Subjects:
IBDV
infectious bursal disease
bursa of Fabricius
inbred lines
chickens
Online Access:https://www.mdpi.com/1999-4915/13/5/933

Internet

https://www.mdpi.com/1999-4915/13/5/933

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