Pharmacokinetics and Metabolism of 4R-Cembranoid.

Pharmacokinetics and Metabolism of 4R-Cembranoid.

4R-cembranoid (4R) is a natural cyclic diterpenoid found in tobacco leaves that displays neuroprotective activity. 4R protects against NMDA, paraoxon (POX), and diisopropylfluorophosphate (DFP) damage in rat hippocampal slices and against DFP in rats in vivo. The purpose of this study was to examine...

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Bibliographic Details
Main Authors: Wanda Vélez-Carrasco, Carol E Green, Paul Catz, Anna Furimsky, Kathleen O'Loughlin, Vesna A Eterović, P A Ferchmin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4374761?pdf=render

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