High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia

Summary: Aging is associated with tissue-level changes in cellular composition that are correlated with increased susceptibility to disease. Aging human mammary tissue shows skewed progenitor cell potency, resulting in diminished tumor-suppressive cell types and the accumulation of defective epithel...

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Bibliographic Details
Main Authors: Fanny A. Pelissier Vatter, Denis Schapiro, Hang Chang, Alexander D. Borowsky, Jonathan K. Lee, Bahram Parvin, Martha R. Stampfer, Mark A. LaBarge, Bernd Bodenmiller, James B. Lorens
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471830490X