A Bright and Colorful Future for G-Protein Coupled Receptor Sensors

A Bright and Colorful Future for G-Protein Coupled Receptor Sensors

Neurochemicals have a large impact on brain states and animal behavior but are notoriously hard to detect accurately in the living brain. Recently developed genetically encoded sensors obtained from engineering a circularly permuted green fluorescent protein into G-protein coupled receptors (GPCR) p...

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Bibliographic Details
Main Authors: Luca Ravotto, Loïc Duffet, Xuehan Zhou, Bruno Weber, Tommaso Patriarchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neurotransmitters
neuromodulators
GPCRs
fluorescent proteins
genetically encoded sensors
in vivo imaging
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00067/full

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