Lithium chloride prevents glucocorticoid-induced osteonecrosis of femoral heads and strengthens mesenchymal stem cell activity in rats
Background:. Accumulating evidence suggests that lithium influences mesenchymal stem cell (MSC) proliferation and osteogenic differentiation. As decreased bone formation in femoral heads is induced by glucocorticoids (GCs), we hypothesized that lithium has a protective effect on GC-induced osteonecr...
Main Authors: | Yue-Lei Zhang, Zhen-Zhong Zhu, Le-Cheng Zhang, Gang Wang, Li-Shao Guo |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2021-09-01
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Series: | Chinese Medical Journal |
Online Access: | http://journals.lww.com/10.1097/CM9.0000000000001530 |
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