A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1

It is now established that cholesterol oxidation products (oxysterols) are involved in several events underlying Alzheimer's disease (AD) pathogenesis. Of note, certain oxysterols cause neuron dysfunction and degeneration but, recently, some of them have been shown also to have neuroprotective...

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Bibliographic Details
Main Authors: Gabriella Testa, Erica Staurenghi, Serena Giannelli, Simona Gargiulo, Michela Guglielmotto, Massimo Tabaton, Elena Tamagno, Paola Gamba, Gabriella Leonarduzzi
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718302714