Ziyuglycoside II alleviates cyclophosphamide-induced leukopenia in mice via regulation of HSPC proliferation and differentiation

Ziyuglycoside II alleviates cyclophosphamide-induced leukopenia in mice via regulation of HSPC proliferation and differentiation

Ziyuglycoside II (ZGS II) is a major bioactive ingredient of Sanguisorbae officinalis L., which has been widely used for managing myelosuppression or leukopenia induced by chemotherapy or radiotherapy. In the current study, we investigated the pro-hematopoietic effects and underlying mechanisms of Z...

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Bibliographic Details
Main Authors: Haihong Fang, Xinxu Xie, Peng Liu, Ying Rao, Yaru Cui, Shilin Yang, Jun Yu, Yingying Luo, Yulin Feng
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ziyuglycoside II
Leukopenia
Hematopoietic stem and progenitor cells
Proliferation
RNA-seq
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220310544

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