PCR in the First Oropharynx Aspirate of the Newborn: A Possible Source for Identification of Congenital Infection Agents
We present a case of prenatal diagnosis of congenital rubella. After birth, in addition to traditional serologic and clinical examinations to confirm the infection, we could identify the virus in the "first fluid aspirated from the oropharynx of the newborn", using polimerase chain reactio...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universidade de São Paulo
1997-11-01
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| Series: | Revista do Instituto de Medicina Tropical de São Paulo |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651997000600011 |
| Summary: | We present a case of prenatal diagnosis of congenital rubella. After birth, in addition to traditional serologic and clinical examinations to confirm the infection, we could identify the virus in the "first fluid aspirated from the oropharynx of the newborn", using polimerase chain reaction (PCR). We propose that this first oropharynx fluid (collected routinely immediately after birth) could be used as a source for identification of various congenital infection agents, which may not always be easily identified by current methods<br>Relatamos um caso de diagnóstico pré-natal de rubéola congênita. Após o nascimento, além da confirmação feita através do exame físico e sorológico do recém-nascido, o vírus também pode ser demonstrado no primeiro fluido aspirado da orofaringe do recém-nascido, utilizando-se a reação em cadeia da polimerase (PCR). Sugerimos que este fluido (colhido rotineiramente no momento da reanimação neonatal) possa ser utilizado na pesquisa de outros agentes infecciosos, que não são facilmente identificados por outros métodos |
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| ISSN: | 0036-4665 1678-9946 |