“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer

Among paraneoplastic neurologic disorders (PND), opsoclonus-myoclonus syndrome, so-called “dancing eye syndrome,” is a rare disorder combining multivectorial eye movements, involuntary multifocal myoclonus, and cerebellar ataxia. Although several paraneoplastic antibodies against postsynaptic or cel...

Full description

Bibliographic Details
Main Authors:	S. Laroumagne, Xavier Elharrar, B. Coiffard, J. Plojoux, H. Dutau, D. Breen, P. Astoul
Format:	Article
Language:	English
Published:	Hindawi Limited 2014-01-01
Series:	Case Reports in Medicine
Online Access:	http://dx.doi.org/10.1155/2014/545490

id	doaj-22c19be878244148bcde9c82a6b1e4bc
record_format	Article
spelling	doaj-22c19be878244148bcde9c82a6b1e4bc2020-11-24T23:50:09ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/545490545490“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung CancerS. Laroumagne0Xavier Elharrar1B. Coiffard2J. Plojoux3H. Dutau4D. Breen5P. Astoul6Department of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, AP-HM-Hôpital Nord, Chemin des Bourrely, 13326 Marseille Cedex 20, FranceDepartment of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, AP-HM-Hôpital Nord, Chemin des Bourrely, 13326 Marseille Cedex 20, FranceDepartment of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, AP-HM-Hôpital Nord, Chemin des Bourrely, 13326 Marseille Cedex 20, FranceDepartment of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, AP-HM-Hôpital Nord, Chemin des Bourrely, 13326 Marseille Cedex 20, FranceDepartment of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, AP-HM-Hôpital Nord, Chemin des Bourrely, 13326 Marseille Cedex 20, FranceDepartment of Respiratory Medicine, University Hospitals Galway, Galway, IrelandDepartment of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, AP-HM-Hôpital Nord, Chemin des Bourrely, 13326 Marseille Cedex 20, FranceAmong paraneoplastic neurologic disorders (PND), opsoclonus-myoclonus syndrome, so-called “dancing eye syndrome,” is a rare disorder combining multivectorial eye movements, involuntary multifocal myoclonus, and cerebellar ataxia. Although several paraneoplastic antibodies against postsynaptic or cell-surface antigens have been reported, usually most patients are serum antibody negative. We report a 65-year-old patient with opsoclonus-myoclonus syndrome revealing a small-cell lung carcinoma. If serologic antineuronal anti-body screening was negative, autoantibodies against glutamic acid decarboxylase (anti-GAD) were positive. Despite the specific anticancer treatment and high dose corticosteroids, the patient developed a severe and progressive encephalopathy and died 10 days later.http://dx.doi.org/10.1155/2014/545490
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	S. Laroumagne Xavier Elharrar B. Coiffard J. Plojoux H. Dutau D. Breen P. Astoul
spellingShingle	S. Laroumagne Xavier Elharrar B. Coiffard J. Plojoux H. Dutau D. Breen P. Astoul “Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer Case Reports in Medicine
author_facet	S. Laroumagne Xavier Elharrar B. Coiffard J. Plojoux H. Dutau D. Breen P. Astoul
author_sort	S. Laroumagne
title	“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer
title_short	“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer
title_full	“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer
title_fullStr	“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer
title_full_unstemmed	“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer
title_sort	“dancing eye syndrome” secondary to opsoclonus-myoclonus syndrome in small-cell lung cancer
publisher	Hindawi Limited
series	Case Reports in Medicine
issn	1687-9627 1687-9635
publishDate	2014-01-01
description	Among paraneoplastic neurologic disorders (PND), opsoclonus-myoclonus syndrome, so-called “dancing eye syndrome,” is a rare disorder combining multivectorial eye movements, involuntary multifocal myoclonus, and cerebellar ataxia. Although several paraneoplastic antibodies against postsynaptic or cell-surface antigens have been reported, usually most patients are serum antibody negative. We report a 65-year-old patient with opsoclonus-myoclonus syndrome revealing a small-cell lung carcinoma. If serologic antineuronal anti-body screening was negative, autoantibodies against glutamic acid decarboxylase (anti-GAD) were positive. Despite the specific anticancer treatment and high dose corticosteroids, the patient developed a severe and progressive encephalopathy and died 10 days later.
url	http://dx.doi.org/10.1155/2014/545490
work_keys_str_mv	AT slaroumagne dancingeyesyndromesecondarytoopsoclonusmyoclonussyndromeinsmallcelllungcancer AT xavierelharrar dancingeyesyndromesecondarytoopsoclonusmyoclonussyndromeinsmallcelllungcancer AT bcoiffard dancingeyesyndromesecondarytoopsoclonusmyoclonussyndromeinsmallcelllungcancer AT jplojoux dancingeyesyndromesecondarytoopsoclonusmyoclonussyndromeinsmallcelllungcancer AT hdutau dancingeyesyndromesecondarytoopsoclonusmyoclonussyndromeinsmallcelllungcancer AT dbreen dancingeyesyndromesecondarytoopsoclonusmyoclonussyndromeinsmallcelllungcancer AT pastoul dancingeyesyndromesecondarytoopsoclonusmyoclonussyndromeinsmallcelllungcancer
_version_	1725479793431937024

“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer

Similar Items