A robust co-localisation measurement utilising z-stack image intensity similarities for biological studies.

BACKGROUND: Co-localisation is a widely used measurement in immunohistochemical analysis to determine if fluorescently labelled biological entities, such as cells, proteins or molecules share a same location. However the measurement of co-localisation is challenging due to the complex nature of such...

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Bibliographic Details
Main Authors: Yinhai Wang, Craig Ledgerwood, Claire Grills, Denise C Fitzgerald, Peter W Hamilton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281864?pdf=render