Inflammatory Mediators and Insulin Resistance in Obesity: Role of Nuclear Receptor Signaling in Macrophages

Inflammatory Mediators and Insulin Resistance in Obesity: Role of Nuclear Receptor Signaling in Macrophages

Visceral obesity is coupled to a general low-grade chronic inflammatory state characterized by macrophage activation and inflammatory cytokine production, leading to insulin resistance (IR). The balance between proinflammatory M1 and antiinflammatory M2 macrophage phenotypes within visceral adipose...

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Bibliographic Details
Main Authors:	Lucía Fuentes, Tamás Rőszer, Mercedes Ricote
Format:	Article
Language:	English
Published:	Hindawi Limited 2010-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2010/219583

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