Transient Expression of Lumbrokinase (PI239) in Tobacco (Nicotiana tabacum) Using a Geminivirus-Based Single Replicon System Dissolves Fibrin and Blood Clots

Transient Expression of Lumbrokinase (PI239) in Tobacco (Nicotiana tabacum) Using a Geminivirus-Based Single Replicon System Dissolves Fibrin and Blood Clots

Lumbrokinases, a group of fibrinolytic enzymes extracted from earthworm, have been widely used to prevent and treat various cardiovascular diseases. They specifically target fibrin to effectively degrade thrombi without major side effects. Plant expression systems are becoming potential alternative...

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Bibliographic Details
Main Authors:	Alexia Dickey, Nan Wang, Edwin Cooper, Lauren Tull, Drew Breedlove, Hugh Mason, Dehu Liu, Kevin Yueju Wang
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	Evidence-Based Complementary and Alternative Medicine
Online Access:	http://dx.doi.org/10.1155/2017/6093017

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