From the low-density lipoprotein receptor–related protein 1 to neuropathic pain: a potentially novel target

From the low-density lipoprotein receptor–related protein 1 to neuropathic pain: a potentially novel target

Abstract. This review describes the roles of the low-density lipoprotein receptor–related protein 1 (LRP-1) in inflammatory pathways, nerve nerve degeneration and -regeneration and in neuropathic pain. Induction of LRP-1 is able to reduce the activation of the proinflammatory NFκB-mediated pathway a...

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Bibliographic Details
Main Authors: Patricia García-Fernández, Nurcan Üçeyler, Claudia Sommer
Format: Article
Language:English
Published: Wolters Kluwer 2021-01-01
Series:PAIN Reports
Online Access:http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000898

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