Role for sumoylation in systemic inflammation and immune homeostasis in Drosophila larvae.

To counter systemic risk of infection by parasitic wasps, Drosophila larvae activate humoral immunity in the fat body and mount a robust cellular response resulting in encapsulation of the wasp egg. Innate immune reactions are tightly regulated and are resolved within hours. To understand the mechan...

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Bibliographic Details
Main Authors: Indira Paddibhatla, Mark J Lee, Marta E Kalamarz, Roberto Ferrarese, Shubha Govind
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3009591?pdf=render