1,3-Oxazol-4-ylphosphonium salts as new non-peptide inhibitors of furin

1,3-Oxazol-4-ylphosphonium salts as new non-peptide inhibitors of furin

A series of novel triphenylphosphonium derivatives of 1,3-oxazole containing at C2 and C5-positions electron withdrawing or electron-donating groups were synthesized and characterized by 1H, 31P NMR and IR spectroscopy, element analysis and chromato-mass spectrometry. These compounds were found to b...

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Bibliographic Details
Main Authors: T. V. Osadchuk, V. K. Kibirev1,2, O. V. Shybyryn, A. V. Semyroz, Ye. S. Velihina, Е. R. Abdurakhmanova, V. S. Brovarets
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2019-08-01
Series:Ukrainian Biochemical Journal
Subjects:
furin
inhibitors
mechanism of inhibition
oxazole derivatives
triphenylphosphonium salts
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2019/06/Osadchuk_4_19.pdf

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http://ukrbiochemjournal.org/wp-content/uploads/2019/06/Osadchuk_4_19.pdf

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