Telomerase prevents accelerated senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts

<p>Abstract</p> <p>Fibroblasts derived from glucose-6-phosphate dehydrogenase (G6PD)-deficient patients display retarded growth and accelerated cellular senescence that is attributable to increased accumulation of oxidative DNA damage and increased sensitivity to oxidant-induced se...

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Bibliographic Details
Main Authors: Wu Yi-Hsuan, Cheng Mei-Ling, Ho Hung-Yao, Chiu Daniel, Wang Tzu-Chien V
Format: Article
Language:English
Published: BMC 2009-02-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/18