Quantitative Cross Polarization Magic-Angle Spinning NMR Spectroscopy in Solids

• Main Authors: LIANG Li-xin, DENG Feng, HOU Guang-jin
• Format: Article
• Language: zho
• Published: Science Press 2020-03-01
• Series: Chinese Journal of Magnetic Resonance
• Subjects: solid state nmr; quantitative nmr; quantitative cross polarization; relaxation time
• Online Access: http://121.43.60.238/bpxzz/EN/10.11938/cjmr20192779

The combination of cross polarization and magic-angle spinning (CP/MAS), is a routine technique for signal enhancement in solid-state nuclear magnetic resonance (NMR) spectrum. With CP/MAS, the acquisition efficiency of solid-state NMR experiments can be improved greatly. However, the enhanced signal is not quantitative according to the different CP dynamics dominated by several factors including heteronuclear dipolar couplings, spin-lattice relaxation times in the rotating frame, molecular motions, number of around abundant spins, and so on. Over the years, numerous efforts have been made to obtain quantitative CP/MAS spectroscopy. This review firstly briefly illustrated the introduction of CP and CP dynamics, and then a series of quantitative NMR methods based on CP were introduced, including ramped-amplitude CP (RAMP-CP), multiple-contact CP, quantification of CP (QCP), Lee-Goldburg frequency modulated CP (LG-FMCP) and quantitative CP (QUCP).